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GUIDOR® Bioresorbable Matrix Barrier

A line of translucent, resorbable barrier membranes with a unique, multi-layer design that facilitates periodontal tissue integration.

  • 100% synthetic with predictable resorption1
  • Can be cut and shaped to precisely cover the defect site
  • Becomes malleable within seconds at body temperature, making it easy to handle and control
  • Available in various shapes and sizes, with and without ligatures for your guided bone and tissue regeneration cases

Each unit contains one dental membrane.

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Availability: In stock

Material Composition

GUIDOR® Bioresorbable Matrix Barrier is made with polylactides blended with a citric acid ester – compounds that have a history of more than 20 years of use in the food and medical industry. Whether you are completing guided bone regeneration (GBR) or guided tissue regeneration (GTR) cases, this fully resorbable dental membrane was designed with predictable performance and ease of use in mind.

Animated Technology Overview Video

Multi-Layer Design

GUIDOR® Bioresorbable Matrix Barrier uses a unique multi-layer matrix design that stabilizes the wound site, aids in the early integration with gingival connective tissues and effectively impedes epithelial downgrowth.

External Layer:
The rectangle perforations of the External Layer (1) allows for gingival connective tissue cells to proliferate the matrix.

Inner Space:
The spacers maintain the inner space (2) between the External (1) and Internal (3) Layers which allow the gingival connective tissue to integrate into the matrix and create the best conditions for regeneration.

Internal Layer:
Minute perforations in the Internal Layer (3) prevent passage of the gingival connective tissue. This innovative design allows nutrients and oxygen to permeate, enabling precise guided tissue and bone regeneration.

Predictable Resorbability1

GUIDOR® Bioresorbable Matrix Barrier is designed to maintain a barrier function for a minimum of 6 weeks, during which time the structure of the matrix is maintained. Afterwards, the product resorbs within a predictable span of time and is gradually replaced by periodontal tissue.

After 6 Weeks:
The design of GUIDOR Matrix Barrier is easily recognized, including the matrix sealing bar (2), matrix ligature (3), external layer (5), internal layer (6) and inner space (4).
The connective tissue (1) surrounds the matrix and penetrates the inner space (4) of the matrix. Newly formed periodontal ligament (8) and alveolar bone (7) are seen in close contact with the material (6).

After 3 Months:
Resorption has started. The degrading matrix (9) is surrounded by dense connective tissues. Newly formed bone (10) is seen next to the matrix (9) as well as large amounts of cementum (11) with inserting collagen fibers.

After 6 Months:
No GUIDOR® Matrix Barrier material is visibly detected. The new attachment comprised of periodontal ligaments (12) and cementum (11) has formed between the new alveolar bone (10) and root surface.

After 24 Months:
No traces of GUIDOR Matrix Barrier remain, indicating the complete resorption of the matrix and restoration of the tissues.

1. Lundgren D, Mathisen T, Gottlow J. The development of a bioresorbable barrier for guided tissue regeneration. J Swed Dent Assoc 1994; 86: 741-756

GUIDOR® Bioresorbable Matrix Barrier offers a combination of control, handling, and predictability:

  • Can be cut and shaped to precisely cover the defect site
  • Becomes malleable within seconds at body temperature, making it easy to handle and control
  • Available in multiple sizes and shapes, with and without ligatures
  • Can be used with your choice of bone grafting material

Leaving GUIDOR® Bioresorbable Matrix Barrier Exposed

In cases where primary closure is not achievable, the GUIDOR Matrix Barrier may be left exposed provided the membrane is securely tucked under the flap and sutures are placed over it. The dental membrane tends to resorb more quickly following exposure than if fully submerged.

Clinical Case: GBR Case with GUIDOR Matrix Barrier left exposed during healing

The patient was a 63-year-old male with an unremarkable medical history. The mandibular right first molar (tooth #30) was deemed hopeless due to a combined endodontic-periodontal lesion. Treatment plan included tooth extraction, matrix barrier and implant placement.

Clinical case using GUIDOR Matrix Barrier

Instructions for Use (IFU)

Prior to handling products, clinicians should review the Instructions for Use (IFU) for product information, indications, contraindications, precautions, potential adverse effects, and handling directions. The IFU for GUIDOR® Bioresorbable Matrix Barrier is dependent on the configuration: Guided Bone Regeneration (GBR) and Guided Tissue Regeneration (GTR).

Language: English, French, Spanish
GBR Instructions for Use - For use with Item # 5081, 5090

Language: English, French, Spanish
GTR Instructions for Use – For use with Item # 5000, 5010, 5020, 5030, 5040, 5050, 5060

Indications

  • GBR Indications: To aid in bone regeneration and augmentation in oral surgery for extraction socket site preservation, immediate implant placement at time of extraction or delayed placement when additional bone regeneration is desired, ridge augmentation, sinus elevation, and stable barrier for the containment of bone grafting materials.
  •  
  • GTR Indications: For the surgical treatment of periodontal defects, to aid in the regeneration and integration of periodontal tissue components. GTR congurations can also be used as an adjunct in periodontal surgical treatment to supplement the reparative process following scaling and root planing for: Class II furcations, intrabony defects, and recession type defects.

Precautions

GUIDOR® Bioresorbable Matrix Barrier is not intended for use in defects other than those stated under Indications for Use. The GUIDOR Matrix Barrier has not been clinically tested for extensive bone augmentation; for use in the treatment of failing implants; in patients with any systemic disorder or disease that involves an unacceptable increase in post operative risk for complications; and in pediatric patients, pregnant or nursing women.

Possible Adverse Effects

  • GBR Indications: Possible complications following any oral surgery include thermal sensitivity, flap sloughing, some loss of crestal bone height, abscess formation, infection, pain, swelling, and complications associated with the use of anesthesia. As with any type of surgical therapy, the patient may experience discomfort for a few days.
  •  
  • GTR Indications: Possible complications following any oral surgery include thermal sensitivity, gingival recession, flap sloughing, resorption or ankylosis of the treated root, some loss of crestal bone height, abscess formation, infection, pain, swelling, gingival irregularities, and complications associated with the use of anesthesia. As with any type of surgical therapy, the patient may experience minor discomfort for a few days.

The GUIDOR® Bioresorbable Matrix Barrier was the first resorbable, synthetic membrane introduced to the U.S. market, and has been successfully used in thousands of guided bone regeneration and guided tissue regeneration cases.

Surgical Technique Video

Drs. Myron and Marc Nevins demonstrate guided bone regeneration (GBR) and guided tissue regeneration (GTR) surgical techniques using GUIDOR Matrix Barrier.

GBR Procedure: Ridge Preservation using GUIDOR Matrix Barrier [7:51 minutes]

The patient is in excellent medical health with no contradictions for dental care. The mandibular right canine was deemed hopeless due to a root resorption lesion on the lingual surface with bone loss on the mesial surface. Treatment includes tooth extraction and ridge preservation using flap management and barrier membrane.

Ridge Preservation Procedure

 

GTR Case: Gingival Augmentation using GUIDOR Matrix Barrier [11:06 minutes]

This surgical video focuses on the treatment of adjacent defects of gingival recession occurring between maxillary left second bicuspid and lateral incisor. The goal of the augmentation procedure is to provide root coverage and augment the zone of keratinized tissue specifically above the maxillary left canine where only the mucosal margin is present. Treatment includes flap management, papilla preservation, root preparation, and placement of the barrier membrane.

Gingival Augmentation Procedure

Scientific Publications

GUIDOR® Bioresorbable Matrix Barrier is clinically proven with over 100 successful scientific studies. The safety and efficacy of the GUIDOR Matrix Barrier has been well documented in clinical research, and in thousands of private practice patients. The product has been tested in humans and primates, in-vivo and in-vitro.

Recent Publications

Rosen, Paul. Purposeful Exposure of a Polylactic Acid Barrier to Achieve Socket Preservation for Placement of Dental Implants: Case Series Report. Compendium for Continuing Education 34.1 (2013).

Fugazzotto, Paul. The Role of Guided Tissue Regenerative Therapy in Today's Clinical Practice. J Impl & Adv Clin Dent 2011 (1);3; 1: 33-45.

Rosen, Paul. The Combined Use of Allograft and a Polylactic Acid Barrier for GTR and GBR Efforts: 2 Case Reports. J Impl & Adv Clin Dent 2010 (7); 2; 7: 55-63.

For a more extensive list of scientific publications, visit Scientific Publications for GUIDOR Matrix Barrier

GUIDOR® Bioresorbable Matrix Barrier is available in various shapes and sizes, with and without ligatures.

Each unit contains one membrane.

Configuration Type Product Size Product Image Item #
Guided Bone Regeneration (GBR) P6 – Rectangle, 20.0 x 28.0 mm 5081
Guided Bone Regeneration (GBR) P3 – Rectangle, 15.0 x 20.0 mm 5090
Guided Tissue Regeneration (GTR) MC – Molar Curved, 19.8 x 15.0 mm 5000
Guided Tissue Regeneration (GTR) DC – Double Curved, 16.1 x 22.6 mm 5020
Guided Tissue Regeneration (GTR) PPS-R – Perio Plastic Regular, 10.0 x 12.7 mm 5050
Guided Tissue Regeneration (GTR) MSL – Molar Straight Large, 15.0 x 14.2 mm 5060